Nerve Reconstruction Using Processed Nerve Allograft in the U.S. Military

ABSTRACT Background Processed nerve allograft (PNA) is an alternative to autograft for the reconstruction of peripheral nerves. We hypothesize that repair with PNA in a military population will have low rate meaningful recovery (M ≥ 3) because frequency blasting mechanisms and large zones injury. Methods A retrospective review Registry Avance Nerve Graft Evaluating Utilization Outcomes Reconstruction Peripheral Discontinuities database was conducted at Walter Reed Consortium. All adult active duty patients who underwent any complete injuries augmented visit were included. Motor strength sensory function reported as consensus from multidisciplinary testing accordance British Medical Research Council. Results total 23 service members 25 (3 22 mixed motor/sensory) PNA. The average age 30 years majority male (96%). most common injury sciatic (28%) complex mechanism (gunshot, blast, compression, avulsion). defect 77 mm. Twenty-four percent achieved motor recovery. Longer follow-up correlated improved postoperative (r = 0.49 P .03). Conclusions had gaps. Despite (27.3%), gaps motor/sensory nerves are difficult treat, further research needed determine if would achieve superior results. Type study/Level evidence Therapeutic, Level III